Fatty Liver Disease is characterized by the buildup of fat in liver cells. When fat accumulation is not due to excessive alcohol consumption, it is referred to as Non-Alcoholic Fatty Liver Disease (NAFLD). If NAFLD progresses and leads to liver inflammation, it is known as Non-Alcoholic Steatohepatitis (NASH). Both conditions can affect liver function and overall health.
Fatty Liver Disease is increasingly common, with NAFLD affecting approximately 25% of the global population. NASH is less common but is a growing concern due to its potential to lead to serious liver complications. In the United States, Fatty Liver Disease is one of the most common causes of liver disease, with experts estimating that about 24% of adults have nonalcoholic fatty liver disease (NAFLD).
Diagnosis is typically made through blood tests, liver function tests, imaging studies such as ultrasound or MRI, and sometimes liver biopsy to assess the extent of liver damage.
Yes, in many cases, lifestyle changes such as weight loss, improved diet, and increased physical activity can reverse NAFLD and prevent the progression to NASH. Early intervention is key to reversing the disease.
Adopting a healthy diet low in saturated fats and sugars, regular exercise, and weight loss are crucial in managing and potentially reversing NAFLD and NASH. Reducing alcohol intake is also recommended.
While there are no specific medications approved for NAFLD or NASH, medications to manage related conditions such as diabetes, high cholesterol, or hypertension can be beneficial. In some cases, clinical trials may offer new treatment options.
If left untreated, Fatty Liver Disease can progress to more serious conditions, including liver fibrosis, cirrhosis, and liver cancer. Regular monitoring and management are essential to prevent these complications.
Some common symptoms of fatty liver disease include severe tiredness, weakness, weight loss, yellowing of the skin or eyes, spiderlike blood vessels on the skin, and long-lasting itching.
Risk factors include being overweight, having high blood fat levels, diabetes or prediabetes, and high blood pressure.
